Travis A. Babola

The paper shows that co-tuned neuronal ensembles in the auditory cortex rapidly rebalance their activity in response to stimulation to maintain consistent perceptual processing.

The paper defines deep layer 6 excitatory neurons in mouse neocortex by comparing molecular, transcriptional, morphological, and transgenic approaches, identifying a core population with distinct connectivity and developmental properties.

This paper presents a method to reduce hearing loss in transgenic mice by crossing them with congenic B6.CAST-Cdh23Ahl+mice, improving auditory research accuracy.

The paper shows that in deaf mice lacking connexin 26, cochlear supporting cells retain spontaneous activity, preserving early auditory circuit development despite structural cochlear changes.

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

This study shows that cochlear spontaneous activity during development is crucial for proper auditory circuit maturation, affecting frequency tuning and neural gain.

The paper shows that purinergic signaling via ATP release from inner supporting cells drives spontaneous activity in the auditory system from birth to hearing onset, promoting coordinated neural firing in frequency-specific circuits.

This study shows that purinergic signaling in cochlear supporting cells regulates hair cell excitability by altering extracellular space volume through K+ dynamics.