Cancer BiologybioRxivPreprint
BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia
Laura López-Hernández, Stephanie J. Crowley, Sara Cea-Sánchez…·Gonzalo Millán-Zambrano
This study identifies BCLAF1 as a regulator linking RNA splicing to ATF4-dependent metabolic adaptation in AML, showing its role in sustaining leukemic cell survival and sensitivity to venetoclax.