Author

Domenico Ignoti

University of Turin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Isaia BarbieriiD· 2 shared Luca PandolfiniiD· 2 shared Stefano GustincichiD· 2 shared Adriano SettiiD· 1 shared Alessio MengaiD· 1 shared Angela Maria SavinoiD· 1 shared Angelo D’AngeloiD· 1 shared Anna Mary Benedetti· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Isaia BarbieriORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TGS1 mediates mRNA 5'-cap trimethylation to promote oxidative phosphorylation in acute myeloid leukaemia.

Valentina Miano, Giovanna Carrà, Maxim Bouvet, Jan Lj. Miljković, Vincent Paupe, Chak Shun Yu, Domenico Ignoti, Sara Milioni, Lorenzo Manfreda, Daniele Viavattene, Anna Mary Benedetti, Angelo D’Angelo, Luan Shi-Lu, Davide Acquarone, Valeria Poli, , Isaia Barbieri

This study identifies TGS1 as a methyltransferase that modifies mRNAs encoding mitochondrial proteins in AML, promoting oxidative phosphorylation and cell survival, and shows its potential as a therapeutic target.

bioRxiv · Oct 19, 2026 · PreprintCancer Biology

BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia

Laura López-Hernández, Stephanie J. Crowley, Sara Cea-Sánchez, Ricardo de Arellano, Neetij Krishnan, Patrick Toolan-Kerr, Lynn S. White, Domenico Ignoti, Emily Soto-Hidalgo, Stefano Gustincich, Román González‐Prieto, Luca Pandolfini, Isaia Barbieri, Patricia Altea‐Manzano, Jeffrey A. Magee, , Gonzalo Millán-Zambrano

This study identifies BCLAF1 as a regulator linking RNA splicing to ATF4-dependent metabolic adaptation in AML, showing its role in sustaining leukemic cell survival and sensitivity to venetoclax.

bioRxiv · Jan 22, 2026 · PreprintCancer Biology