Author

Laura López-Hernández

Centro Andaluz de Biología Molecular y Medicina RegenerativaORCID 0000-0003-3649-3110Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

Gonzalo Millán-ZambranoiD· 3 shared Luca PandolfiniiD· 2 shared Patrick Toolan-KerriD· 2 shared Ricardo de ArellanoiD· 2 shared Ananda Ayyappan Vadusevan· 1 shared Andrés AguileraiD· 1 shared Diego Polanco-AlonsoiD· 1 shared Domenico Ignoti· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Gonzalo Millán-ZambranoORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 23, 2026

H3K37me1 couples transcription with DNA replication origin selection

Ricardo de Arellano, Patrick Toolan-Kerr, Iria Domínguez-García…·Gonzalo Millán-Zambrano

This study identifies H3K37me1 as a histone modification that regulates DNA replication origin selection by limiting MCM2-7 association with transcribed chromatin.

DOI 10.64898/2026.06.22.733675

humanChIP-seq

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Cancer BiologybioRxivPreprintJan 22, 2026

BCLAF1 links RNA splicing to ATF4-dependent metabolic adaptation in acute myeloid leukemia

Laura López-Hernández, Stephanie J. Crowley, Sara Cea-Sánchez…·Gonzalo Millán-Zambrano

This study identifies BCLAF1 as a regulator linking RNA splicing to ATF4-dependent metabolic adaptation in AML, showing its role in sustaining leukemic cell survival and sensitivity to venetoclax.

1 citation

humanmouse

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Molecular BiologybioRxivPreprintJan 22, 2024

Topological regulation of the estrogen transcriptional response by ZATT-mediated inhibition of TOP2B activity

José Terrón-Bautista, María del Mar Martínez-Sánchez, Laura López-Hernández…·Felipe Cortés‐Ledesma

The paper identifies ZATT-mediated inhibition of TOP2B as a mechanism regulating estrogen-induced transcriptional changes through DNA supercoiling.

1 citation

humanDNA methylation

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