Charles T.S. Puerner

A strain-specific metabolic role for the UDP-glucose 4-epimerase Uge3 in Aspergillus fumigatus virulence

The paper identifies a strain-specific metabolic role for Uge3 in H-MORPH A. fumigatus strains, linking it to virulence and central carbon metabolism.

Insights into Aspergillus fumigatus morphogenesis and pathogenesis through the putative lipid transporter ArvA

This study identifies arvA as critical for Aspergillus fumigatus morphogenesis and antifungal drug susceptibility but shows it is not required for virulence in murine models.

Dynamic cytoplasmic fluidity during morphogenesis in a human fungal pathogen

The paper observes decreased molecular crowding during yeast to filamentous growth transition in C. albicans, linked to reduced ribosome concentration and increased cytoplasmic volume.

A ceramide synthase is important for filamentous fungal biofilm morphology and antifungal drug resistance

This study identifies a ceramide synthase, barA, as important for biofilm morphology and antifungal drug resistance in Aspergillus fumigatus.

Transcriptional analysis of developing Aspergillus fumigatus biofilms reveals metabolic shifts required for biofilm maintenance

This study uses transcriptomics to identify metabolic shifts and genes important for maintaining mature A. fumigatus biofilms.

Giant transposons promote strain heterogeneity in a major fungal pathogen

This study identifies giant transposons called Starships in Aspergillus fumigatus that generate genomic and phenotypic heterogeneity across strains.

CF-Seq, An Accessible Web Application for Rapid Re-Analysis of Cystic Fibrosis Pathogen RNA Sequencing Studies

CF-Seq provides a web tool for re-analyzing CF pathogen RNA-seq data, enabling efficient filtering, visualization, and hypothesis generation across multiple studies.