Ian M. Thornell

This paper shows that in utero ivacaftor treatment rescues multiple organ defects in CFTR-G551D pigs, improving pancreatic, gallbladder, and vas deferens function.

This study shows that combining CFTR modulators with amphotericin B increases HCO3- secretion and airway surface liquid pH in CF airway epithelia more than either treatment alone.

The paper shows that modified amphotericin B derivatives improve ASL pH in CF airway epithelia better than amphotericin B itself.

The paper compares gene expression and function of airway cell types in small and large porcine airways, finding distinct transcriptomes and functional roles.