Artyom A. Egorov

The paper isolates and characterizes six new E. coli-infecting phages from Kazakhstan, expanding a phage collection and demonstrating phage research in high school education.

This study presents cryo-EM structures of UG10 enzymes and elucidates their enzymatic mechanism involving RT and primase domains, showing their anti-phage activity.

The paper isolates and characterizes five Escherichia coli phages, identifies their defense system sensitivities, and highlights the educational value of phage isolation training.

The paper introduces iLund4u, an algorithm to systematically annotate hyper-variability hotspots in phage genomes and plasmids, identifying 13.7K hotspots and 171K diverse protein families across 873K phage and 696K plasmid sequences.

The paper introduces DefenseFinder, a resource for antiphage defense systems, including a web service, wiki, and databases with structure predictions.

LoVis4u is a tool for visualizing genomic loci alignments, generating publication-ready PDFs from GenBank or GFF data, with customizable features for prokaryotic genomes.

This study identifies and characterizes two Escherichia coli TAC systems that mediate antiphage defense by recognizing phage proteins and modifying mRNA to inhibit translation.

The paper analyzes transcriptomic and proteomic data to identify tissue-specific expression of translation machinery components and highlights sexual dimorphism in translation factors.

uORF4u annotates conserved upstream open reading frames (uORFs) in 5' upstream sequences of proteins or homologues using evolutionary conservation.

The paper investigates how a standard knockout procedure in yeast affects the expression of neighboring genes at the translational level, revealing significant changes in protein abundance.