Marco E. Mechan Llontop

This study shows that bacterial metabolites affect insulin signaling in C. elegans by altering acid sphingomyelinase expression.

This study identifies Massetolide F, a bacterial cyclic lipopeptide, as a molecule that suppresses dauer arrest in C. elegans by inducing acid sphingomyelinase expression.

This study identifies N1-APA, a noncanonical polyamine produced by bacteria, as a bioactive metabolite that antagonizes animal mitochondrial function and macrophage activation.