Kelsie M. Nauta

Bacterial metabolites alter the consequences of reduced insulin signaling in C. elegans via increasing the expression of the acid sphingomyelinase asm-3.

This study shows that bacterial metabolites affect insulin signaling in C. elegans by altering acid sphingomyelinase expression.

Bacterial-derived cyclic lipopeptides suppress dauer arrest in C. elegans

This study identifies Massetolide F, a bacterial cyclic lipopeptide, as a molecule that suppresses dauer arrest in C. elegans by inducing acid sphingomyelinase expression.

Oocyte mitochondria link maternal environment to offspring phenotype

The paper identifies a role for oocyte mitochondrial electron transport chain remodeling in linking maternal environment to offspring metabolism and survival.

Evaluating the Link Between Efflux Pump Expression and Motility Phenotypes in Pseudomonas aeruginosa Treated with Virulence Inhibitors

This paper investigates how virulence inhibitors affect efflux pump expression in Pseudomonas aeruginosa and links this to changes in motility and virulence.

kinact/KI Value Determination for Penicillin-Binding Proteins in Live Cells

The paper develops a whole-cell assay to measure kinact/KI values for PBPs in Streptococcus pneumoniae, showing results consistent with in vitro data and supporting its validity as an in vivo method.

A noncanonical polyamine from bacteria antagonizes animal mitochondrial function

This study identifies N1-APA, a noncanonical polyamine produced by bacteria, as a bioactive metabolite that antagonizes animal mitochondrial function and macrophage activation.