Author

Ján Kriška

Czech Academy of SciencesORCID 0000-0001-5684-5828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Denisa KirdajováiD· 4 shared Miroslava AnděrováiD· 4 shared Jana TurečkováiD· 3 shared Tomáš KnotekiD· 3 shared Eva RohlováiD· 2 shared Jan KubovčiakiD· 2 shared Lucie JanečkováiD· 2 shared Lukáš ValihrachiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersNeuroscience

Denisa KirdajováORCID

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4 papers

Recent·Most cited

NeuroscienceCommunications BiologyPeer-reviewedAug 26, 2026

Canonical Wnt signaling controls the fate and plasticity of NG2 glia in the healthy and ischemic adult mouse cortex

Tomáš Knotek, Lucie Janečková, Ján Kriška…·Vladimír Kořínek

This study shows Wnt signaling regulates NG2 glia fate in adult mouse cortex, promoting neuronal conversion while impairing oligodendrocyte maturation after ischemic injury.

DOI 10.1038/s42003-026-10813-9

mousebulk RNA-seq

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NeurosciencebioRxivPreprintAug 11, 2025

PU.1-driven enrichment enables microglia profiling from frozen brain tissue using the high-throughput Smart-seq3xpress method

Dominika Dostalova, Pavel Abaffy, Eva Rohlová…·Lukáš Valihrach

The paper introduces a method to profile microglia from frozen brain tissue using PU.1 as a marker and Smart-seq3xpress, showing improved transcriptomic data compared to standard protocols.

DOI 10.1101/2025.08.11.669607

mousescRNA-seq

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NeuroscienceGliaPeer-reviewedSep 29, 2023

Astrocyte-like subpopulation of NG2 glia in the adult mouse cortex exhibits characteristics of neural progenitor cells and is capable of forming neuron-like cells after ischemic injury

Lucie Janečková, Tomáš Knotek, Ján Kriška…·Vladimír Kořínek

The paper identifies an astrocyte-like NG2 glia subpopulation in adult mouse cortex that shows neurogenic potential and can form neuron-like cells after ischemic injury.

25 citations

mousebulk RNA-seq

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GenomicsCell ReportsPeer-reviewedJun 1, 2020

Decoding the transcriptional response to ischemic stroke in young and aged mouse brain

Peter Androvic, Denisa Kirdajová, Jana Turečková…·Lukáš Valihrach

The paper analyzes RNA-Seq data from young and aged mice after ischemic stroke to identify age-related transcriptional changes and inflammatory responses.

118 citationstop 3%

mousebulk RNA-seq

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