Author

Miroslava Anděrová

Czech Academy of SciencesORCID 0000-0002-9030-4571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 5 Research Focus:cell type annotation· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Denisa KirdajováiD· 5 shared Ján KriškaiD· 4 shared Jana TurečkováiD· 3 shared Lukáš ValihrachiD· 3 shared Pavel AbaffyiD· 3 shared Tomáš KnotekiD· 3 shared Daniel ŽuchaiD· 2 shared Eva RohlováiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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5 shared papersNeuroscience

Denisa KirdajováORCID

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5 papers

Recent·Most cited

Canonical Wnt signaling controls the fate and plasticity of NG2 glia in the healthy and ischemic adult mouse cortex

Tomáš Knotek, Lucie Janečková, Ján Kriška, Denisa Kirdajová, Alice Foltynova, Jan Kubovčiak, Kateřina Večerková, Makoto Mark Taketo, Michal Kolář, Miroslava Anděrová, Vladimír Kořínek

This study shows Wnt signaling regulates NG2 glia fate in adult mouse cortex, promoting neuronal conversion while impairing oligodendrocyte maturation after ischemic injury.

Communications Biology · Aug 26, 2026Peer-reviewedNeuroscience

PU.1-driven enrichment enables microglia profiling from frozen brain tissue using the high-throughput Smart-seq3xpress method

Dominika Dostalova, Pavel Abaffy, Eva Rohlová, Ján Kriška, Tomáš Knotek, Jana Turečková, Denisa Kirdajová, Miroslava Anděrová, Lukáš Valihrach

The paper introduces a method to profile microglia from frozen brain tissue using PU.1 as a marker and Smart-seq3xpress, showing improved transcriptomic data compared to standard protocols.

bioRxiv · Aug 11, 2025 · PreprintNeuroscience

Spatiotemporal transcriptomic map of ischemic brain injury

Daniel Žucha, Pavel Abaffy, Denisa Kirdajová, Daniel Jirák, Mikael Kubista, Miroslava Anděrová, Lukáš Valihrach

This study maps the spatiotemporal transcriptomic changes in mouse brain tissue after ischemic injury, revealing glial cell responses and their role in neuroinflammation.

Proceedings of the National Academy of Sciences · Nov 5, 2024Peer-reviewedNeuroscience

Astrocyte-like subpopulation of NG2 glia in the adult mouse cortex exhibits characteristics of neural progenitor cells and is capable of forming neuron-like cells after ischemic injury

Lucie Janečková, Tomáš Knotek, Ján Kriška, Zuzana Heřmanová, Denisa Kirdajová, Jan Kubovčiak, Linda Berková, Jana Turečková, Sara Camacho Garcia, Kateřina Galušková, Michal Kolář, Miroslava Anděrová, Vladimír Kořínek

The paper identifies an astrocyte-like NG2 glia subpopulation in adult mouse cortex that shows neurogenic potential and can form neuron-like cells after ischemic injury.

Glia · Sep 29, 2023Peer-reviewedNeuroscience

Decoding the transcriptional response to ischemic stroke in young and aged mouse brain

Peter Androvic, Denisa Kirdajová, Jana Turečková, Daniel Žucha, Eva Rohlová, Pavel Abaffy, Ján Kriška, Martin Valný, Miroslava Anděrová, Mikael Kubista, Lukáš Valihrach

The paper analyzes RNA-Seq data from young and aged mice after ischemic stroke to identify age-related transcriptional changes and inflammatory responses.

Cell Reports · Jun 1, 2020Peer-reviewedGenomics