Author

Lulu Xue

University of PennsylvaniaORCID 0000-0001-5719-1336Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lulu Xue1 paper · ShanghaiTech University

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:multiome· 2 Research Focus:differential expression· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Michael J. MitchelliD· 4 shared Junchao XuiD· 3 shared Adele S. RicciardiiD· 2 shared Ajay S. ThatteiD· 2 shared Drew WeissmaniD· 2 shared Hannah C. GeisleriD· 2 shared Ryann A. JosephiD· 2 shared Xuexiang HaniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersBioengineering

Michael J. MitchellORCID

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4 papers

Recent·Most cited

BioengineeringProceedings of the National Academy of SciencesPeer-reviewedMay 26, 2026

Plug-and-play assembly of biodegradable ionizable lipids for potent mRNA delivery and gene editing in vivo

Xuexiang Han, Ying Xu, Adele S. Ricciardi…·Michael J. Mitchell

This study develops a combinatorial chemistry approach to create biodegradable ionizable lipids for efficient mRNA delivery and gene editing in vivo.

13 citationstop 1%

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringAdvanced MaterialsPeer-reviewedJan 28, 2026

High-throughput in vivo screening using barcoded mRNA identifies lipid nanoparticles with extrahepatic tropism for cancer immunotherapy

Alex G. Hamilton, Ajay S. Thatte, Junchao Xu…·Michael J. Mitchell

15 citationstop 1%

𝕏 PostBluesky

BioengineeringbioRxivPreprintNov 25, 2025

Mineralized Tissue-Targeting Expression System for Local Control of Gene Expression

Jingyi Liu, Qinyuan Chen, Il‐Chul Yoon…·Kyle H. Vining

This paper develops a gene expression system targeting mineralized tissues using bisphosphonate lipids, demonstrating enhanced RNA delivery and local therapeutic effects in bone regeneration and inflammation.

DOI 10.1101/2025.11.25.690451

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringbioRxivPreprintNov 12, 2025

Anti-CD38-Targeted Piperazine-Derived Lipid Nanoparticles Overcome Hepatic Clearance for mRNA Delivery to Multiple Myeloma Cells In Vivo

Christian G. Figueroa‐Espada, Hannah C. Geisler, Ryann A. Joseph…·Michael J. Mitchell

This study develops anti-CD38 lipid nanoparticles for targeted mRNA delivery to multiple myeloma cells, improving tumor targeting and reducing hepatic accumulation.

DOI 10.1101/2025.11.12.687398

𝕏 PostBluesky