Joanna Poźniak

This study maps the heterogeneity of human melanoma metastases across brain, liver, and lung using single-nucleus RNA sequencing, revealing organ-specific immune and stromal adaptations.

This study shows that IFNγ suppresses lymphatic vessel growth and metastasis by altering metabolism and immune function in melanoma.

The paper identifies NK cells as contributors to resistance to anti-PD1 therapy in immune-excluded melanomas using single-cell RNA sequencing and spatial proteomics.

The paper develops software to infer copy number and detect single nucleotide variants in spatial transcriptomics data, applied to skin cancer to reveal genetic patterns and clonal populations.