Author

Matthew A. Loberg

Vanderbilt University Medical CenterORCID 0000-0001-5840-4591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Quanhu ShengiD· 3 shared Vivian Lee WeissiD· 3 shared Barbara A. MurphyiD· 2 shared Courtney J. PhiferiD· 2 shared Eric C. HuangiD· 2 shared Ethan N. LeeiD· 2 shared George Jing XuiD· 2 shared Heather A. HartmanniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Quanhu ShengORCID

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3 papers

Recent·Most cited

An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations

Matthew A. Loberg, George Jing Xu, Sheau‐Chiann Chen, Hua‐Chang Chen, Claudia C. Wahoski, Kailey P. Caroland, Megan L. Tigue, Heather A. Hartmann, Jean‐Nicolas Gallant, Courtney J. Phifer, Andres A. Ocampo, Dayle K. Wang, Reilly G. Fankhauser, Kirti A. Karunakaran, Chia-Chin Wu, , Vivian Lee Weiss

This study integrates single-cell and spatial transcriptomics to identify prognostic fibroblast subpopulations in thyroid cancer progression.

JCI Insight · Jan 1, 2026Peer-reviewedCancer Biology

Overnutrition directly impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations

Jessica Rampy, Alejandra Paola Torres-Manzo, Kendra Hoffsmith, Matthew A. Loberg, Quanhu Sheng, Federico Salas-Lucia, Antonio Carlos Bianco, Rafael Arrojo e Drigo, Huiying Wang, Vivian Lee Weiss, Nancy Carrasco

This study shows overnutrition causes hypothyroidism in mice by impairing thyroid hormone biosynthesis and utilization, despite thyroid adaptations, and finds a link between BMI and thyroid vascularization in humans.

bioRxiv · Mar 31, 2025 · PreprintPhysiology

Tenascin-C potentiates Wnt signaling in thyroid cancer

Heather A. Hartmann, Matthew A. Loberg, George Jing Xu, Anna Schwarzkopf, Sheau‐Chiann Chen, Courtney J. Phifer, Kailey P. Caroland, Hua-Chang Chen, Diana Diaz, Megan L. Tigue, Amanda B. Hesterberg, Jean‐Nicolas Gallant, Sophia M. Shaddy, Quanhu Sheng, James L. Netterville, , Vivian Lee Weiss

This study shows that Tenascin-C enhances Wnt signaling and promotes invasion and metastasis in thyroid cancer through in vitro and in vivo experiments.

Endocrinology · Feb 5, 2025Peer-reviewedCancer Biology