Author

Brenton Cavanagh

Royal College of Surgeons in IrelandORCID 0000-0002-1582-5756Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aaron Philips· 1 shared Aideen E. RyaniD· 1 shared Aisling Y. CoughlaniD· 1 shared Alexandra J Emerson· 1 shared Amaya Sanz‐Rodriguez· 1 shared Amra Batool· 1 shared Andrew J. RoeiD· 1 shared Andrew M. ShawiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

Aaron Philips

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyNature MetabolismPeer-reviewedJul 23, 2026

Mitochondrial metabolism is a key determinant of chemotherapy sensitivity in Colorectal Cancer

Deborah Y. Moss, Connor N. Brown, Andrew M. Shaw…·Emma M. Kerr

This study identifies mitochondrial metabolism as a key factor in 5-fluorouracil resistance in colorectal cancer and shows that targeting mitochondrial Complex I can enhance chemotherapy effectiveness.

9 citationstop 1%

humanbulk RNA-seq

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ImmunologyBiomaterialsPeer-reviewedApr 15, 2026

Metabolic Reprogramming of Human Macrophages Drives the Formation of Hybrid M1/M2 Pro-Regenerative Extracellular Vesicles

Cansu Görgün, Paula A. Klavina, Carolina Martins…·David A. Hoey

This study shows that metabolic reprogramming of human macrophages using DASA-58 generates hybrid M1/M2 extracellular vesicles with pro-regenerative properties that enhance angiogenesis and osteogenesis.

5 citationstop 1%

humanbulk RNA-seq

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NeurosciencebioRxivPreprintOct 8, 2019

Potent and lasting seizure suppression by systemic delivery of antagomirs targeting miR-134 timed with blood-brain barrier disruption

Cristina Ruedell Reschke, Luiz Fernando Almeida Silva, Vamshidhar R. Vangoor…·David Clifford Henshall

This study shows that systemic delivery of Ant-134, timed with BBB disruption after status epilepticus, suppresses seizures in mice with long-lasting effects.

1 citation

mouseexperimental assay

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