Jordan M. Welker

Disruption of a CCR5-like immunoglobulin gene is linked to plague susceptibility in black-footed ferrets

The paper identifies a disrupted CCR5-like immunoglobulin gene in black-footed ferrets linked to increased susceptibility to plague caused by Yersinia pestis.

Assemblatron: An Automated Workflow for High-Throughput Assembly of Big-DNA Libraries

The paper introduces an automated workflow for high-throughput assembly of large DNA libraries using yeast-based methods, achieving high success rates in assembling diverse DNA constructs.

Zebrafish Cre/lox regulated UFlip alleles generated by CRISPR/Cas targeted integration provide cell-type specific conditional gene inactivation

The paper develops a CRISPR/Cas9-based method to generate Cre/lox regulated conditional gene alleles in zebrafish, enabling cell-type specific gene inactivation.

Endogenous zebrafish neural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration

This paper generates zebrafish Cre drivers by integrating a 2A-Cre transgene into proneural genes, resulting in functional Cre expression in specific cell populations.

multicrispr: fast gRNA designer enables prime editing and parallel targeting of thousands of targets

multicrispr is a gRNA design tool that enables efficient and specific gRNA creation for CRISPR-based applications like Prime Editing and large-scale screening.

Expanding The CRISPR Toolbox With Mad7 In Zebrafish And Human Cells

This paper characterizes ErCas12a, a new CRISPR/Cas system, showing it enables efficient DNA repair and gene integration in zebrafish and human cells.

GeneWeld: a method for efficient targeted integration directed by short homology

GeneWeld enables efficient and precise targeted integration in multiple species using CRISPR/Cas9 with minimal homology arms.