Jennifer L. Small-Saunders

Double Mutations in Plasmodium falciparum Kelch13 drive resistance to next-generation artemisinin derivatives in malaria parasites

This study identifies a novel K13 double mutation conferring resistance to ozonide antimalarials in Plasmodium falciparum parasites with existing artemisinin resistance.

Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malaria

This paper models recombination's impact on multi-drug resistance evolution in malaria, showing that most recombinant genotypes arise from multi-clonal infections and that ACT strategies reduce treatment failures and delay resistance.

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

This study identifies DMT1 and a chromosome 12 locus, including FtsH1, as novel contributors to Plasmodium falciparum resistance to quinine, alongside the known pfcrt gene.