Stuart C. Howes

This study uses structural biology techniques to show that ER stress in yeast increases inactive ribosomes and modulates elongation factors, suggesting modest translation inhibition as a stress response.

This study shows taxanes induce conformational changes in microtubules, releasing GEF-H1 and activating RhoA signaling, leading to actin remodeling.

The paper identifies oxygen-induced tubular nanocompartments in Pyrococcus furiosus using proteomics and cryo-EM, revealing their structure and role in ROS protection.

The paper investigates the interactions of ciliary tip proteins and their role in microtubule dynamics, finding that they form structures that slow and processively elongate microtubules.

The paper shows that microtubule lattice spacing affects kinesin-1 binding, with expanded lattices preferentially bound by kinesin-1.