Oded Rechavi

The paper shows that dysfunction in maternal scavenger cells disrupts systemic RNA homeostasis, leading to transgenerational germline tumors in C. elegans.

The paper demonstrates that planarians can maintain long-term heritable gene silencing through a two-phase RNAi mechanism independent of canonical RdRPs.

The paper presents a stage-specific transcriptomic dataset of C. elegans distal tip cells, identifying molecular programs driving leader cell invasion and revealing new genes involved in this process.

The paper shows neuronal small RNAs protect germline integrity and prevent heat-induced sterility in lab Caenorhabditis elegans by modulating thermotolerance and countering domestication effects.

The paper identifies PALS-22 as a regulator of AGO expression in C. elegans, showing its role in balancing immunity and germline health through modulation of RNAi and epigenetic inheritance.

The paper shows that AFD neuron dysfunction in C. elegans alters transposable element (TE) expression, with Mirage transposase induction being a consistent phenotype, while Tc1 mutagenesis depends on background factors.

The paper shows that temperature perception in C. elegans can drive transgenerational epigenetic inheritance through RNAi factors and small RNAs.

This study creates a gene expression atlas for C. elegans sexes, identifying sex-specific genes and their roles in development and physiology.

This study shows that cold temperatures and lithium salt delay forgetting of olfactory memories in C. elegans by modulating membrane properties and the diacylglycerol pathway in specific neurons.

This study shows that small RNAs can be inherited transgenerationally in C. elegans without nuclear factors or chromatin changes, mediated by ZNFX-1 and germ granules.

RNAlysis provides a user-friendly software for RNA sequencing analysis without coding, enabling customizable pipelines for data processing, visualization, and interpretation.

The paper quantifies trans-splicing in C. elegans mRNAs using Nanopore sequencing, revealing terminal hairpins in non-trans-spliced mRNAs.

The paper shows ASI sensory neurons control the CEP-1/p53 DNA damage response in PGCs via TGF-beta signaling, reducing inherited mutations.

The paper shows that inherited small RNAs in C. elegans regulate sexual attraction and outcrossing rates across generations, influencing population genetics under stress.

The paper shows that stress resets transgenerational small RNA inheritance in C. elegans by reducing heritable small RNA levels and involving MAPK pathway factors, SKN-1, and MET-2 methyltransferase.

The paper identifies three inheritance rules governing transgenerational small RNA responses in C. elegans and shows they predict developmental rate and stress resistance.

The paper shows that transgenerational small RNA inheritance in C. elegans can occur independently of germ granules in some mutants, but depends on ancestral germ granule function and HRDE-1.

The paper shows that H3K9me3 is not universally required for RNAi inheritance in C. elegans, but its role depends on the gene being silenced.

This paper engineers Toxoplasma gondii to deliver therapeutic proteins to the CNS by fusing them to the parasite's secretory proteins, demonstrating potential for intracellular delivery of treatments for neurological disorders.

This study shows that growing C. elegans in liquid media leads to intergenerational changes in size, which are not fully reversible and may involve epigenetic mechanisms.

This study tests the Independence of Irrelevant Alternatives in C. elegans using olfactory chemotaxis assays, showing that neuronal constraints can lead to bounded rationality.

WorMachine automates phenotypic analysis of C. elegans by identifying worms, extracting features, and quantifying signals, demonstrating effectiveness in multiple assays.

The paper shows that small RNAs in apomictic dandelion lineages reflect drought stress and salicylic acid treatment from two generations ago, indicating transgenerational epigenetic effects.