Shiqiang Gao

The paper identifies a KCR1 variant, C29D, that maintains stable potassium selectivity and provides reliable optogenetic inhibition across species and conditions.

This study develops a K+-selective channelrhodopsin for transcranial optogenetic inhibition of neuronal activity, showing reduced seizure activity in mouse models.

The paper shows that calcium-triggered apoplastic ROS bursts balance gravity and mechanical signals to regulate root bending during soil navigation.

This study shows a patient-derived monoclonal antibody rapidly inhibits N-methyl-D-aspartate receptors directly, suggesting potential therapeutic strategies using antigen-binding fragments.

The paper investigates six membrane transporters in Plasmodium falciparum, finding four essential for asexual development and one essential for gametocytogenesis.

The paper demonstrates the use of ChR2-XXL and GtACR1 in primary rat cortical neurons to manipulate neuronal firing patterns through high current optogenetic channels.