Cell BiologybioRxivPreprint
Centrosome-centromere capture range, rather than centrosome arrangement, determines multipolar chromosome segregation pattern after whole-genome duplication
DOI 10.64898/2026.08.24.746909
Author
Guang Yang
Hokkaido UniversityORCID 0000-0001-6293-283XUnclaimed ORCID profile · follow to get notified of new preprints
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Recent·Most cited
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Profiling cell proliferation after whole-genome duplication in human cells
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Sister chromatid separation determines the proliferative properties upon whole-genome duplication via homologous chromosome arrangement
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This study shows that mitotic slippage and cytokinesis failure, two mechanisms of whole-genome duplication, differentially affect post-WGD cell viability through distinct chromosome segregation patterns.
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1 citation