Author

Jens Panse

RWTH Aachen UniversityORCID 0000-0001-6316-3112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:deconvolution· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Steffen KoschmiederiD· 2 shared Alessia PiergentiliiD· 1 shared André EsseriD· 1 shared Anne Kaiser· 1 shared Axel ChoidasiD· 1 shared Barbara Zieger· 1 shared Bert KlebliD· 1 shared Carina Birkhofer· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Steffen KoschmiederORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 18, 2026

PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies

Xuhuang Fu, Anne Kaiser, Payal Chawla…·Martin Zenke

This paper identifies PDE3A-SLFN12 molecular glues as a novel therapeutic target for KIT D816V-driven mast cell malignancies, showing their efficacy in killing multiple KIT D816V cell types and synergy with tyrosine kinase inhibitors.

DOI 10.64898/2026.08.13.744624

humanproteomics

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Molecular BiologybioRxivPreprintJul 31, 2024

Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H

Swagata Konwar, Sophie Schroda, Jessika Kleindienst…·Karsten Häffner

This study identifies TSP-1 as a FH-independent inhibitor of the alternative complement pathway, showing its role in vasculitis by modulating complement activation and NETosis.

DOI 10.1101/2024.07.31.606000

humanexperimental assay

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Molecular BiologyClinical ChemistryPeer-reviewedNov 8, 2017

Leukocyte counts based on site-specific DNA methylation analysis

Joana Frobel, Tanja Božić, Michael Lenz…·Wolfgang Wagner

The paper develops a method to estimate leukocyte counts using DNA methylation analysis, achieving similar precision to conventional methods with advantages in sample handling.

29 citations

humanDNA methylation

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