Ayato Takada

This study identifies key ACE2 residues that influence sarbecovirus infectivity in African Rhinolophus bats and reports novel ACE2 sequences from R. simulator and R. blasii.

This study identifies montanine as a potent antiviral compound that inhibits RNA viruses by targeting translational elongation and GCN1-related stress responses.

This study uses human respiratory organoids to show that a cattle-derived H5N1 isolate replicates efficiently but suppresses innate immune responses, explaining its mild clinical presentation in humans.

The paper uses an agent-based model to quantify how specific NPC1 SNPs affect filovirus entry efficiency in vitro, finding that D508N, P424A, and S425L reduce entry efficiency for both Ebola and Marburg viruses.