Zhigang Lu

This study analyzes histone modifications, chromatin accessibility, and transcription in Schistosoma mansoni gonads to uncover the histone code governing gene expression and reproductive development.

The paper presents the first spatial transcriptome of the liver fluke Fasciola hepatica, identifying gene expression profiles and markers for eight tissues, with focus on vaccine candidates, drug targets, and resistance genes.

The paper performs single-cell transcriptomics on the first intra-molluscan stage of Schistosoma mansoni to identify key cell type regulators and their biological processes.

This study provides a comprehensive transcriptomic analysis of Schistosoma mansoni across eight life stages, revealing sex-specific gene expression patterns and developmental transitions.

This study identifies daily transcriptomic rhythms in Schistosoma mansoni, revealing rhythmic gene expression patterns and their potential relevance to parasite survival and drug targets.

This study analyzes the transcriptome of Schistosoma mansoni developing eggs to identify genes involved in pathogenesis and life cycle progression.

The paper assembles the chromosomes of Schistosoma mansoni, revealing insights into the evolution of its ZW sex-determination system through gene annotation and synteny analysis.

This study creates a single-cell RNA sequencing atlas of the early intra-mammalian stage of Schistosoma mansoni, identifying gene expression profiles and validating cell markers.

This study performs a meta-analysis of RNA-seq data to identify genes responsible for life stage-dominant functions in Schistosoma mansoni.

The paper presents a web portal that provides gene expression data across all life stages of Schistosoma mansoni, along with functional annotations and tools for data analysis and visualization.