Peter L. Voyvodic

This study uses single-cell electrophysiology to show verapamil disrupts bacterial membrane energetics by selectively dissipating the electrical component of the proton motive force, distinct from classical protonophores.

This paper introduces minireporters for monitoring gene expression and peptide production in cell-free systems, reducing DNA length and synthesis costs while maintaining reliable output.

The paper evaluates matrix effects on cell-free biosensor performance in clinical samples and introduces a method to mitigate these effects using a modified RNase inhibitor.

PeroxiHUB is a cell-free biosensing platform that detects metabolites by converting them into H2O2 using enzymatic transducers, enabling modular and scalable detection.

This paper develops exonuclease-deficient cell-free extracts and optimized buffers to enable robust expression from unprotected linear DNA without additional protection strategies.

This paper introduces a synthetic receptor platform for detecting liver dysfunction biomarkers using engineered bacteria, achieving sensitive and portable diagnostics.

The paper introduces metabolic perceptrons for binary classification of metabolite combinations using computational models and experimental validation in synthetic biological circuits.

This paper introduces hybrid cell-free biosensors that expand the range of detectable chemicals by combining synthetic metabolic cascades with transcription factor-based networks.