Matthew P. Challis

Proximity labelling of the BAK macropore uncovers a new role for SLC35A4-MP in mitochondrial dynamics

This study uses proximity labeling to identify proteins near the BAK pore during apoptosis, revealing SLC35A4-MP's role in modulating mitochondrial dynamics.

Characterization of human Metaxin proteins reveals functional diversification of SAM37 homologs MTX1 and MTX3

This study investigates the functional differences between MTX1 and MTX3, showing that their loss leads to distinct mitochondrial phenotypes and that both depend on MTX2 for stability.

PfK13-associated artemisinin resistance slows drug activation and enhances antioxidant defence, which can be overcome with sulforaphane.

This study identifies PfK13 mutations as drivers of artemisinin resistance by enhancing antioxidant defenses, which can be counteracted by sulforaphane.