Author

Linda E. Fong

Calico Life SciencesORCID 0000-0001-6833-7185Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Charles L. SawyersiD· 2 shared Dana Pe’eriD· 2 shared Elisa de StanchinaiD· 2 shared Eric RosiekiD· 2 shared HuiYong ZhaoiD· 2 shared Ning FaniD· 2 shared Wenfei Kang· 2 shared Zhenghao CheniD· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Charles L. SawyersORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 23, 2026

✦ In-depth digest

Extracellular matrix regulates lineage plasticity in prostate cancer through YAP/TEAD

Teng Han, Zhen Sun, Matthew Lange…·Charles L. Sawyers

Loss of extracellular matrix-integrin signaling switches off YAP/TEAD and lets prostate adenocarcinoma organoids turn neuroendocrine; LATS inhibition reverses it, and combined YAP, NOTCH and AR inhibition fully reprograms them.

4 citations

mousehuman

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Cancer BiologybioRxivPreprintJul 31, 2026

IL-1β/IL-6 signaling circuit in the tumor microenvironment drives prostate cancer development

Young Sun Lee, Jimmy L. Zhao, Agnieszka Chryplewicz…·Charles L. Sawyers

This study identifies an IL-1β/IL-6 signaling circuit in the tumor microenvironment that drives prostate cancer progression from pre-invasive to invasive stages.

DOI 10.64898/2026.07.30.741572

mousebulk RNA-seq

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Systems BiologybioRxivPreprintJul 19, 2018

Systems analysis by mass cytometry identifies susceptibility of latent HIV-infected T cells to targeting of p38 and mTOR pathways

Linda E. Fong, Victor L. Bass, Serena Spudich, Kathryn Miller‐Jensen

1 citation

humanproteomics

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