Martine Tétreault

This study identifies ancestry-specific immune signatures in Parkinson's disease through rare variant analysis in Montreal and Guadeloupe cohorts, revealing divergent molecular pathways associated with disease.

The paper identifies neuronal lipid droplets as conserved structures that regulate energy homeostasis with sex-biased effects in flies and mice.

The paper constructs a genetic reference panel for the Quebec population using whole-genome sequencing and GWAS to improve phenotype-genotype association discovery.

This study uses whole-exome sequencing to identify rare genetic variants associated with sleepwalking in two cohorts, finding 99 genes enriched in patients and 31 shared genes with rare variants.

This paper identifies bi-allelic AMPD2 variants as a cause of Leigh syndrome, showing they lead to complex V assembly defects and cytosolic purine imbalance.

The paper develops a CRISPR/Cas9 electroporation and single-cell cloning protocol for human myoblasts, achieving high editing success rates and purity.

This study uses single-cell sequencing to analyze peripheral immune cell changes in Parkinson's disease patients, identifying key immune signatures and potential biomarkers.

This study shows that two ketogenic diets improve cognition and metabolic health in Alzheimer's disease mouse models, with distinct effects on peripheral metabolism.

This study investigates RFC1's role in zebrafish cerebellar development, showing its necessity for neural progenitor genomic integrity and neurogenesis.

This study shows TDP-43 stabilizes G3BP1 transcripts via direct binding, and TDP-43 depletion reduces G3BP1 protein levels, contributing to stress granule dysfunction in ALS/FTD.