Olivier Tillement

Hydrogel confinement enables subcutaneous delivery of vesicant antibody-drug conjugates

This paper develops a hydrogel that enables subcutaneous delivery of vesicant antibody-drug conjugates by confining them in a depot, reducing tissue damage while maintaining antitumor efficacy.

Nanomaterials trigger functional responses in primary human immune cells

This study evaluates the effects of nanomaterials on human immune cells, finding that PLGA NPs enhance NK cell function while Si-Gd NPs impair T cell activation.

Targeted Drug Delivery by Radiation-Induced Tumor Vascular Modulation

This paper demonstrates that combining radiation with gold nanoparticles enhances tumor vascular permeability and improves nanodrug delivery in pancreatic cancer.