Lucy Glover

This study uses a genetic screen in Trypanosoma brucei to identify novel kDNA maintenance factors, validates one as a novel replication factor, and provides a prioritized list of candidates.

The paper adapts the SHERLOCK CRISPR-based detection tool for trypanosome species in pigs to improve AAT diagnostics and identify human-infectious trypanosome reservoirs.

The paper identifies phosphorylation sites in response to DNA breaks in Trypanosoma brucei and finds a specific RPA-1 phosphorylation event required for resection at a subtelomeric locus.

The paper investigates how the position of DNA double strand breaks influences gene expression and VSG switching pathway choice in Trypanosoma brucei.

The paper identifies a novel mechanism in trypanosomes where inter-chromosomal interactions between an antigen coding gene and an mRNA splicing locus ensure monogenic antigen expression.

This study shows RAD50 promotes homologous recombination and limits antigenic variation in Trypanosoma brucei by controlling DNA repair mechanisms.