Tatiana Sandoval‐Guzmán

Tissue composition shapes differential skeletal integration strategies during axolotl limb regeneration

The paper shows that tissue composition at the amputation plane influences osteoclast-mediated skeletal resorption and regenerative strategies in axolotl limb regeneration.

Static morphogen scaling enables proportional growth in tissue growth model inspired by axolotl limb regeneration

The paper investigates morphogen scaling mechanisms in axolotl limb regeneration, showing static scaling ensures proportional growth while dynamic scaling does not.

Differential fates of vertebrate Kazald gene quartet, from ancestral roles in skeletogenesis and regeneration to putative innovations in fish and birds

The paper investigates the evolution of the Kazald gene family in vertebrates, identifying its origin and differential roles across species.

Mechanical control of tissue growth during limb regeneration

This study shows that mechanical properties and YAP/TAZ activity influence position-dependent cell proliferation during axolotl limb regeneration.

Axolotl mandible regeneration occurs through mechanical gap closure and a shared regenerative program with the limb

This study shows axolotl mandible regeneration involves gap closure and shares a regenerative program with limb regeneration, occurring more slowly.

Multi-species atlas resolves an axolotl limb development and regeneration paradox

The paper uses a multi-species single-cell atlas to resolve whether axolotls regenerate limbs by re-forming AER cells, finding they do not fully re-form AER but use a novel mesoderm-based program.

Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration

The paper shows that osteoclast-mediated resorption of calcified tissue is essential for successful skeletal integration during axolotl limb regeneration.

In vivo assessment of mechanical properties during axolotl development and regeneration using confocal Brillouin microscopy

This study uses confocal Brillouin microscopy to assess mechanical properties during axolotl limb development and regeneration, finding a gradual increase in cartilage compressibility during these processes.

Post-embryonic development and aging of the appendicular skeleton in Ambystoma mexicanum

This study examines the post-embryonic development and aging of the appendicular skeleton in axolotls, showing continuous ossification and cellular changes throughout life.

The Prrx1 limb enhancer marks an adult population of injury-responsive, multipotent dermal fibroblasts

This study identifies Prrx1 enhancer-positive dermal fibroblasts as injury-responsive, multipotent cells capable of promoting scar-free wound healing.