Daniel A. Starr

The paper shows that the LINC complex and nuclear lamina delay nucleolar assembly in C. elegans embryos by organizing heterochromatin, with CEC-4 playing a key role in suppressing premature nucleoli.

This study identifies a nucleolar-ribosomal axis linking lamin mutations to cytoplasmic biophysical changes in EDMD, revealing a new pathway for laminopathy pathogenesis.

The paper shows UNC-83 isoforms differentially regulate kinesin-1 and dynein to control nuclear migration directionality during development.

This study identifies N2G as an F-actin bundler and kinesin-1 activator that mediates active microtubule-actin crosstalk, crucial for nuclear positioning.

The paper identifies two conserved mechanisms controlling cytoplasmic macromolecular diffusion in C. elegans tissues, involving ribosome concentration and the giant KASH protein ANC-1.

The paper shows that anchoring H3K9-methylated heterochromatin to the nuclear periphery is necessary for P-cell nuclear migration through constrictions in C. elegans, independent of the LINC complex.

The paper identifies FLN-2 as a third pathway mediating P-cell nuclear migration in C. elegans, functioning alongside LINC complexes and CDC-42/actin pathways to maintain nuclear envelope integrity during migration through constricted spaces.

The paper identifies CDC-42 and the Arp2/3 complex as regulators of nuclear migration in C. elegans P-cells, functioning parallel to the LINC complex.

This study identifies mib-1 as essential for forming the nuclear halo in C. elegans sperm through genetic analysis of fer mutations.