Nikolay P. Kandul

The paper develops a split-CRISPR/Cas9 system for sex conversion in Mediterranean fruit flies to improve population control strategies.

This study investigates inheritance bias mechanisms in a CRISPR gene drive in Aedes aegypti, finding two distinct mechanisms: homing in double heterozygous males and meiotic drive.

The paper develops transgenic Drosophila suzukii strains expressing Cas9 with different promoters and terminators to enable efficient gene editing for studying gene function and control strategies.

This paper develops a CRISPR-based sterile insect technique to eliminate Aedes aegypti mosquitoes in controlled environments.

This paper introduces a gene drive called HomeR that efficiently spreads and persists in Drosophila populations by limiting resistance allele accumulation.

This paper introduces a drug-inducible system for sex separation in insects, demonstrating 100% efficiency in Drosophila melanogaster with low fitness costs.

This study evaluates a split homing gene drive in Drosophila to simultaneously target two genes, showing high disruption efficiency but also resistance allele accumulation.

This paper describes a CRISPR-based method called precision guided SIT (pgSIT) that produces 100% sterile male insects, enhancing the scalability and effectiveness of insect population control.