Jared B. Bennett

This study develops split suppression gene drives in Aedes aegypti, showing that inheritance efficiency and reproductive fitness costs must be balanced for effective population suppression.

The paper uses genomic data and simulation modeling to show that Aedes aegypti populations in southern Australia can be eliminated with Wolbachia-infected male releases if rainwater tanks are removed first.

This paper extends close-kin mark-recapture methods to estimate mosquito dispersal parameters and barrier strength using simulations of Aedes aegypti populations.

The paper demonstrates a convertible gene-drive system that transitions from a split-drive to a full-drive element in the spo11 locus, showing similar final introgression levels despite initial slower kinetics.

MGDrivE 2 simulates gene drive systems with seasonal and epidemiological dynamics to predict their impact on disease transmission.

This study tests split gene-drive systems in Drosophila that target essential genes, showing variable copy efficiencies and sex-biased transmission, with outcomes that can be inherently confined.

This paper develops a CRISPR-based sterile insect technique to eliminate Aedes aegypti mosquitoes in controlled environments.

This paper develops a gene-drive rescue system in Anopheles stephensi to efficiently modify mosquito populations for malaria control.

This paper introduces a gene drive called HomeR that efficiently spreads and persists in Drosophila populations by limiting resistance allele accumulation.

The paper introduces a split-gene-drive system that enhances safety and flexibility in CRISPR-based gene drive applications through trans-complementation.

MGDrivE simulates gene drive spread in mosquito populations, showing how different architectures affect population replacement and suppression.