Author

Lindsay Jones Talbot

St. Jude Children's Research HospitalORCID 0000-0001-7409-9873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Adam B. CornwelliD· 1 shared Aditya BarveiD· 1 shared Akshay SharmaiD· 1 shared Bilal A. OmeriD· 1 shared Candise L. TatiD· 1 shared Cliona M. RooneyiD· 1 shared David D. SpenceiD· 1 shared Devyn Hooper· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Adam B. CornwellORCID

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2 papers

Recent·Most cited

Senolytics Restore Hematopoietic Stem Cells Function in Sickle Cell Disease

Aditya Barve, Adam B. Cornwell, Pramika Sriram, Oleg V. Kopyov, Preeti Dabas, Emilia Kooienga, Zakiya Kelley, James D. Johnson, Jacquelyn Myers, Esther A. Obeng, Guolian Kang, Yunusa Olufadi, Terri L. Cain, Lindsay Jones Talbot, David D. Spence, , Shannon McKinney‐Freeman

This study shows senolytics like ABT-263 restore bone marrow function in sickle cell disease by reversing HSC dysfunction and senescence in mice.

bioRxiv · Feb 8, 2025 · PreprintCell Biology

Tunneling CARs: Increasing CAR T tumor infiltration through the overexpression of MMP7 and SPP1

Stacey N. Van Pelt, Mark White, Candise L. Tat, Devyn Hooper, Lindsay Jones Talbot, Rohan Fernandes, Cliona M. Rooney, Bilal A. Omer

This study shows that overexpressing MMP7 and SPP1 improves GD2.CART infiltration into solid tumors, leading to better tumor control and survival in a xenograft model.

bioRxiv · Jan 24, 2025 · PreprintImmunology