Author

Amanda Waddell

Cincinnati Children's Hospital Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

Andrés Vázquez‐TorresiD· 1 shared Ashley L. DunniD· 1 shared Babajide A. OjoiD· 1 shared Bryce Hunt· 1 shared Emily R. MiraldiiD· 1 shared Essam A. Elknawy· 1 shared Hee‐Woong LimiD· 1 shared Javier A. López-RiveraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Andrés Vázquez‐TorresORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis

Babajide A. Ojo, Ying Zhu, Lyong Heo, Sejal R. Fox, Yanli Qiao, Amanda Waddell, Maria E. Moreno‐Fernandez, Marielle Gibson, Tracy Tran, Ashley L. Dunn, Essam A. Elknawy, Neetu Saini, Javier A. López-Rivera, Senad Divanovic, Yuqin Dai, , Michael J. Rosen

This study uses patient-derived colon organoids to identify lipid-related metabolic dysfunction in pediatric ulcerative colitis and shows that PPAR-α inhibition can alleviate metabolic and inflammatory features.

Nature Communications · Dec 10, 2025Peer-reviewedPhysiology

Epithelial-intrinsic nitric oxide synthase 2 sustains host-microbiota dynamics that promote colitis

Seika Hashimoto‐Hill, Bryce Hunt, Sekani Cole, Shikha Negi, Amanda Waddell, Zi F. Yang, Joseph A. Wayman, Nicholas Jay Ollberding, Emily R. Miraldi, Hee‐Woong Lim, Andrés Vázquez‐Torres, Thomas E. Morrison, Lee A. Denson, Theresa Alenghat

This study shows that epithelial nitric oxide synthase 2 (Nos2) influences host-microbiota interactions in IBD by regulating intestinal nitrates and nitrate-metabolizing bacteria, with implications for disease management.

bioRxiv · Sep 23, 2025 · PreprintImmunology