Stephanie L. Borgland

This study shows opioids shift the neuromodulatory effect of LHox/dyn on VTA DA neurons projecting to BLA from inhibitory to excitatory via KOR signaling changes.

The paper identifies a brain serotonin circuit that contributes to age-related decline in physical activity and shows it can be reversed by targeting specific receptors.

The paper investigates how co-released orexin and dynorphin from lateral hypothalamic inputs modulate ventral tegmental area dopamine neuron activity, showing differential effects based on projection targets.

This study examines how short- and long-term high-fat diets affect GABAergic signaling in the lateral orbitofrontal cortex, finding distinct effects on neuronal function and reward processing.

This study shows that obesity reduces inhibitory neurotransmission in the lateral orbitofrontal cortex, leading to inflexible food-seeking behavior in mice.

This study shows that fasting reduces excitability and inhibitory synaptic transmission of tVTA/RMTG GABAergic neurons, potentially allowing disinhibition of dopamine neurons.

This study compares THC and metabolite pharmacokinetics in rats after inhalation vs. injection, finding route-specific differences in brain and blood levels and hypothermic responses.

This study shows that obesity impairs astrocyte function in the orbitofrontal cortex, leading to synaptic deficits that are reversed by N-acetylcysteine.

This study investigates how acute fasting affects excitatory and inhibitory synapses onto VTA dopamine neurons in male and female mice, finding sex-specific changes in synaptic transmission.

This study investigates how mu-opioids affect GABAergic synaptic transmission in distinct subregions of the orbitofrontal cortex, revealing region-specific long-term depression mediated by PV+ interneurons.

This study investigates how ventral striatopallidal neurons modulate orexin/hypocretin neuron activity in response to food and metabolic states, revealing their role in reward-seeking behavior.