Author
University of California, Los AngelesORCID 0000-0001-7642-5046Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Xianfeng Zeng, Xiandong Meng, Allison M. Weakley…·Michael Andrew Fischbach
The paper shows that modifying microbial community composition, specifically overexpressing bile acid metabolic genes in Lactobacillus strains, can alter bile acid pool size and composition in mice.
Aleksandra Mazitova, Jiani Zhu, Richard Rosario Rodrigues…·Ekaterina K. Koltsova
This study shows IL-17RC signaling in the intestine prevents atherosclerosis by controlling microbiota and perivascular innervation, with loss of IL-17RC increasing inflammation and disease.
Emily C. Whang, Alessandra Ferrari, John Paul Kennelly…·Peter Tontonoz
This study shows that vertical sleeve gastrectomy in mice reduces plasma cholesterol without weight loss by enhancing bile acid synthesis and hepatobiliary elimination.
Bethan L. Clifford, Kelsey E. Jarrett, Joan Cheng…·Elizabeth J. Tarling
This study identifies GOLIATH as an E3 ubiquitin ligase that regulates LDLR availability and plasma LDL cholesterol levels by ubiquitinating LDLR and redistributing it away from the plasma membrane.
Nathalie Pamir, Calvin Pan, Deanna L. Plubell…·Aldons Jake Lusis
The paper identifies genetic regulation of HDL proteome variation across mouse strains, revealing coordinated protein regulation and functional diversity in HDL subspecies.