Natália Faraj Murad

Molecular effects of indoor tanning

This study examines the molecular effects of indoor tanning by analyzing mutation patterns in melanocytes from tanning bed users and finds increased mutation burdens and distinct mutational signatures.

Multi-selective RAS(ON) Inhibition Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 and BCL2 Inhibitors in Acute Myeloid Leukemia

This study evaluates RMC-7977, a RAS(ON) inhibitor, showing efficacy against RAS-driven resistance in AML and potential for combination therapies.

RAS pathway activation drives clonal selection and monocytic differentiation in FLT3 and BCL2 inhibitor resistance

The synergistic actions of hydrolytic genes reveal the mechanism of Trichoderma harzianum for cellulose degradation

This study identifies synergistic gene and protein interactions in Trichoderma harzianum for cellulose degradation using transcriptomic and proteomic analyses.

Integrative Genomic Analysis for the Bioprospection of Regulators and Accessory Enzymes Associated with Cellulose Degradation in a Filamentous Fungus (Trichoderma harzianum)

The paper identifies CAZymes, transcription factors, and transporters in Trichoderma harzianum IOC3844 involved in cellulose degradation using genomic, transcriptomic, and exoproteomic data.