Daniel Sauter

This study identifies Regnases as antiviral restriction factors in humans, showing they inhibit RNA viruses but not DNA viruses, with varying substrate selectivity among the four Regnases.

This study identifies APOBEC3B depletion as a driver of L1 element derepression and increased DNA damage in senescent cells through high-throughput sequencing and Ribo-seq analysis.

This paper identifies Trypstatin, a Kunitz-type protease inhibitor that inhibits TMPRSS2 and related proteases, showing broad-spectrum antiviral activity against SARS-CoV-2, influenza, and other respiratory viruses.

This study compares the effects of SARS-CoV-2 early strains and Omicron variants on intestinal barrier function using a human gut epithelial model, finding Omicron causes less damage.

This study shows SARS-CoV-2 infection activates the LTR69 subfamily of endogenous retroviruses, including Dup69, which influences gene expression near PTPRN2 and ENSG00000289418.