Author

Ella N. Hoogenboezem

Vanderbilt UniversityORCID 0000-0001-7697-4336Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Craig L. DuvalliD· 3 shared Adam M AbdulrahmaniD· 2 shared Alexander G. SoretsiD· 2 shared Alexander P LigockiiD· 2 shared Andrew KjariD· 2 shared Ethan S. LippmanniD· 2 shared Joshua C. ParkiD· 2 shared Katrina R SchwenseniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioengineering

Craig L. DuvallORCID

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3 papers

Recent·Most cited

Novel COX-2 Targeted Nanobodies for Molecular Endoscopic Imaging of Colorectal Adenomas

Md. Jashim Uddin, Shu Xu, Michael Goodman, Ansari Mukhtar Aleem, Hiroaki Niitsu, Kristie Lindsay Rose, Brenda C. Crews, Surajit Banerjee, Carlisle R. DeJulius, Ella N. Hoogenboezem, Philip J. Kingsley, Michelle L. Reyzer, Jamie E. Klendworth, Matthew Milad, Shuyang Lin, , Lawrence J. Marnett

This paper develops COX-2-targeted nanobodies for enhanced endoscopic imaging of colorectal adenomas, showing tumor-specific accumulation in vivo.

bioRxiv · May 19, 2026 · PreprintBioengineering

Intravenous lipid-siRNA conjugate mediates gene silencing at the blood-brain barrier and blood-CSF barrier

Alexander G. Sorets, Katrina R Schwensen, Nora Francini, Andrew Kjar, Sarah Lyons, Joshua C. Park, Dillon Palmer, Adam M Abdulrahman, Rebecca P. Cowell, Ketaki A. Katdare, Ella N. Hoogenboezem, Angela Yee‐Moon Wang, Alexander P Ligocki, Rebecca Embalabala, Neil Dani, , Ethan S. Lippmann

This paper demonstrates that an intravenous lipid-siRNA conjugate can deliver gene silencing to brain barriers without affecting parenchymal tissue.

Journal of Controlled Release · Sep 11, 2025Peer-reviewedBioengineering

Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

Alexander G. Sorets, Katrina R Schwensen, Nora Francini, Andrew Kjar, Adam M Abdulrahman, Alena Shostak, Ketaki A. Katdare, Kathleen M. Schoch, Rebecca P. Cowell, Joshua C. Park, Alexander P Ligocki, William T Ford, Lissa Ventura‐Antunes, Ella N. Hoogenboezem, Alex Prusky, , Ethan S. Lippmann

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

Nucleic Acids Research · Jun 20, 2025Peer-reviewedBioengineering