Krisztina Arató

Metabolic control of germ layer proportions through regulation of Nodal and Wnt signalling

The paper shows that glycolytic activity regulates germ layer proportions by modulating Nodal and Wnt signalling in mouse gastrulation.

Axial patterning of gastruloids via diverse cell type compositions

This study investigates how varying proportions of primed and naive ESCs affect gastruloid formation and AP axial patterning, revealing developmental flexibility in mammalian embryogenesis.

Collective fate decisions and cell rearrangements underlie gastruloid symmetry breaking

The paper shows that collective cell fate decisions and mechanical differences drive symmetry breaking in gastruloids through a mechanochemical mechanism.

Dynamics of anteroposterior axis establishment in a mammalian embryo-like system

The paper studies AP axis establishment in gastruloids using scRNA-seq and identifies molecular signatures of germ layer commitment and differences between Bra/T+ and Bra/T- populations.

Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome

This study shows that DYRK1A haploinsufficiency leads to impaired neocortical circuit development, contributing to neurological symptoms in a syndrome related to Down syndrome.

Key role of amino acid repeat expansions in the functional diversification of duplicated transcription factors

The paper investigates the role of amino acid repeat expansions in the functional diversification of duplicated transcription factors following whole genome duplications.