Masataka Yanagawa

The paper studies the behavior of human RTKs using single-molecule imaging and finds that molecular behavior correlates with cell growth regulation.

This study shows that PI(4,5)P2 and ErbB2 levels regulate ErbB receptor oligomerization and kinase activity differently across family members.

This paper develops a NanoBiT-based platform to systematically study multiple layers of GPCR signaling in living cells.

This study uses single-molecule imaging to show that opioid receptors form transient homodimers, with distinct functional effects on signaling and internalization depending on the receptor subtype.

This study uses super-resolution microscopy to show that EGFR and PI(4,5)P2 nanodomains coaggregate before EGF stimulation, and their interaction is regulated by phospholipase Cγ and PI(4,5)P2 levels.

The paper develops a four-color single-molecule imaging system using fluorescent HiBiT peptides to track GPCR dynamics and interactions in living cells.