Cassiano R.A.F. Diniz

This study shows that dopamine from the locus coeruleus, not the ventral tegmental area, is crucial for trace fear conditioning in the hippocampus by enabling memory trace reactivation.

This study shows that a TRKB mutation blocking antidepressant binding does not affect BDNF-stimulated activation or baseline TRKB function, but impairs antidepressant responses.

This study shows that phasic locus coeruleus activity enhances trace fear conditioning by increasing hippocampal dopamine release, which is critical for memory formation.

This study shows that fluoxetine modulates fear memory extinction via Trk-dependent mechanisms in both dorsal and ventral hippocampus, with distinct effects in each subregion.

This study identifies a direct binding of antidepressants to TRKB receptors, revealing a mechanism linking molecular interactions to antidepressant effects.

This study shows anandamide activates TRKB through CB1 and TRPV1 receptors, influencing neuronal migration and behavior in rat cortical cells.