Manuel Valero

Data-driven identification of functional networks in artificial and biological neural networks

This paper introduces MultiPEC, a method to identify neural representations in artificial and biological systems by reducing context prediction error, showing its effectiveness in both CNNs and EEG data.

Inhibitory and disinhibitory VIP IN-mediated circuits in neocortex

The paper identifies four distinct VIP interneuron populations in the neocortex with unique connectivity and responses to neuromodulation, showing specialized roles in cortical circuit regulation.

Id2 GABAergic interneurons: a neglected fourth major group of cortical inhibitory cells

The paper identifies a fourth major group of cortical inhibitory neurons, Id2 GABAergic interneurons, characterized by neurogliaform cells and distinct electrophysiological properties.

Intricate epileptiform discharges affect memory in an Alzheimer's Disease mouse model

The paper investigates how interictal epileptiform discharges (IEDs) affect memory in Alzheimer's Disease mice, finding that IEDs disrupt hippocampal activity and correlate with impaired memory.

Brief synaptic inhibition persistently interrupts firing of fast-spiking interneurons

The paper shows that brief synaptic inhibition can persistently silence fast-spiking interneurons for hundreds of milliseconds, impacting circuit function through disinhibition of pyramidal cells.

Status epilepticus induces chronic silencing of burster and dominance of regular firing neurons during sharp wave-ripples in the mouse subiculum

This study examines how status epilepticus affects sharp wave-ripples in the mouse subiculum, showing increased ripple activity and altered neuronal firing patterns.

Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis

The paper identifies sublayer- and cell-type-specific transcriptional changes in hippocampal sclerosis using single-nucleus and bulk RNA sequencing, revealing distinct neurodegenerative trajectories in superficial CA1 neurons.

Multimodal determinants of phase-locked dynamics across deep-superficial hippocampal sublayers during theta oscillations

The paper identifies mechanisms shaping phase-locked dynamics in hippocampal sublayers using computational models and mouse/rat data.

Proximodistal organization of the CA2 hippocampal area

The paper examines the proximodistal organization of the CA2 hippocampal area in rats, finding distinct synaptic and membrane potential trends along this axis.