Bernardo Rudy

The paper identifies four distinct VIP interneuron populations in the neocortex with unique connectivity and responses to neuromodulation, showing specialized roles in cortical circuit regulation.

The paper investigates whether transcriptomic profiles can predict neuronal firing-rate adaptation across brain regions and species using Patch-seq data.

The paper identifies a fourth major group of cortical inhibitory neurons, Id2 GABAergic interneurons, characterized by neurogliaform cells and distinct electrophysiological properties.

The paper systematically examines the electrophysiological features of four L1 interneuron subtypes in mice and builds computational models to explain their firing patterns.

The paper investigates inhibitory plasticity in mouse auditory cortex, finding that SST+ interneuron inputs show the most potentiation and contribute to decision accuracy under noise.

The paper identifies cell-type specific circuits formed by subtypes of somatostatin interneurons in the cortex through genetic targeting and connectivity analysis.

The paper shows that bottom-up thalamic inputs are essential for establishing top-down connectivity to layer 1 neurogliaform cells in the visual cortex during early development.

The paper shows that cellular birthdate determines laminar and regional specificity of cholinergic projections in the forebrain.

The paper profiles interneurons in primates and rodents to identify evolutionary innovations in brain cell types and their molecular features.

The paper shows how heterosynaptic plasticity calibrates excitatory and inhibitory inputs onto pyramidal neurons to achieve excitatory-inhibitory balance.

This study identifies Rbfox1 as a cell-type-specific splicing regulator that shapes efferent connectivity in cortical interneurons through alternative splicing programs.