Author

Marci Garcia

Pacific Northwest National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Organism:E. coli· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Jordan C. RozumiD· 3 shared Natalie SadleriD· 3 shared Pavlo BohutskyiiD· 3 shared Zachary JohnsoniD· 3 shared Lindsey N Anderson· 2 shared Margaret S. CheungiD· 2 shared Song FengiD· 2 shared Weijun QianiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Jordan C. RozumORCID

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Author profile →

3 papers

Recent·Most cited

Cell State Transitions Drive Transcriptome-Proteome Alignment in a Minimal Photoautotroph

Jordan C. Rozum, Xiaolu Li, Young‐Mo Kim, Zachary Johnson, William Sineath, Marci Garcia, Natalie Sadler, Pavlo Bohutskyi, Margaret Cheung, Wei-Jun Qian, Song Feng

The paper investigates how cell state transitions in Prochlorococcus marinus MED4 affect transcriptome-proteome alignment through regulatory mechanisms involving RpaB and HimA.

bioRxiv · Oct 21, 2026 · PreprintSystems Biology

Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational Modifications under Light Disturbance

Connah Johnson, Aaron Chan, Jordan C. Rozum, August George, Amar D. Parvate, Pavlo Bohutskyi, D. H. Kim, Song Feng, Zachary Johnson, Natalie Sadler, Marci Garcia, Xiaolu Li, Jesse B. Trejo, Ruonan Wu, William Sineath, , Margaret S. Cheung

The paper develops a 4D whole-cell model of Prochlorococcus marinus MED4 to show how spatial organization and redox PTMs regulate carbon fixation under light disturbance.

Biophysical Journal · Aug 26, 2026Peer-reviewedSystems Biology

Extreme genome reduction selectively retains modular regulatory architecture in Prochlorococcus MED4: conserved transcriptional modules reveal core physiological regulatory programs

Zachary Johnson, Natalie Sadler, Marci Garcia, Xiaolu Li, Jordan C. Rozum, Lindsey N Anderson, Tong Zhang, Song Feng, Weijun Qian, Margaret S. Cheung, Pavlo Bohutskyi

This paper identifies conserved transcriptional modules in Prochlorococcus MED4 using RNA-seq data and independent component analysis, revealing core regulatory programs that persist despite extreme genome reduction.

bioRxiv · Apr 19, 2026 · PreprintSystems Biology