Xiaolu Li

The paper develops a 4D whole-cell model of Prochlorococcus marinus MED4 to show how spatial organization and redox PTMs regulate carbon fixation under light disturbance.

ProteoMeter integrates multi-PTM and limited proteolysis data to map proteomic changes to residue level, demonstrating its use in analyzing HCoV-229E infection.

The paper introduces an LLM-driven pipeline for detecting and structurally modeling post-translational modifications using proteomics data.

This paper identifies conserved transcriptional modules in Prochlorococcus MED4 using RNA-seq data and independent component analysis, revealing core regulatory programs that persist despite extreme genome reduction.

This study shows that activating AMPK alpha2 T172 in skeletal muscle improves exercise performance and energy transduction, and its disruption mimics type 2 diabetes features.

This study shows that m6A methylation, regulated by METTL3, controls the innate immune response in β-cells during T1D onset by modulating OAS mRNA stability.