Author

Sven Diederichs

University of FreiburgORCID 0000-0001-7901-4752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Maïwen Caudron‐HergeriD· 2 shared Arminja Nadine KettenbachiD· 1 shared Athina GanneriD· 1 shared Bianca Kaifer· 1 shared Chelsea SawyeriD· 1 shared Chloé TerwagneiD· 1 shared Christina M. KajbaiD· 1 shared Dominic HelmiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Maïwen Caudron‐HergerORCID

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3 papers

Recent·Most cited

An atlas of RNA-dependent proteins in cell division reveals the riboregulation of mitotic protein-protein interactions

Varshni Rajagopal, Jeanette Seiler, Isha Nasa, Simona Cantarella, Jana Theiss, Franziska Herget, Bianca Kaifer, Melina Klostermann, Rainer D. Will, Martin Schneider, Dominic Helm, Julian König, Kathi Zarnack, Sven Diederichs, Arminja Nadine Kettenbach, Maïwen Caudron‐Herger

The paper identifies RNA-dependent proteins in cell division using R-DeeP, revealing new interactions and phosphorylation events involving AURKA, KIFC1, and TPX2.

Nature Communications · Mar 8, 2025Peer-reviewedCell Biology

Saturation Genome Editing Resolves the Functional Spectrum of Pathogenic VHL Alleles

Megan Buckley, Chloé Terwagne, Athina Ganner, Laura Cubitt, Reid A. Brewer, Dong‐Kyu Kim, Christina M. Kajba, N. Forrester, Phoebe Dace, Joachim De Jonghe, Scott T.C. Shepherd, Chelsea Sawyer, Mairead McEwen, Sven Diederichs, Elke Neumann‐Haefelin, , Gregory M. Findlay

This study uses Saturation Genome Editing to functionally assess VHL variants, identifying pathogenic alleles and their mechanisms in cancer.

Nature Genetics · Jul 1, 2024Peer-reviewedGenomics

Refining the pool of RNA-binding domains advances the classification and prediction of RNA-binding proteins

Elsa Wassmer, Gergely Koppány, Malte Hermes, Sven Diederichs, Maïwen Caudron‐Herger

The paper identifies RNA-binding domains and predicts new RNA-binding proteins across species using a composite scoring system and integrates results into a database.

Nucleic Acids Research · Jun 13, 2024Peer-reviewedBioinformatics