Author

Wayne Boucher

University of CambridgeORCID 0000-0001-7969-2334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:Hi-C· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

David LandoiD· 3 shared Brian HendrichiD· 2 shared Ernest D. LaueiD· 2 shared Nicola ReynoldsiD· 2 shared Xiaoyan MaiD· 2 shared Aleks PonjaviciD· 1 shared Aleksandra Jartseva· 1 shared Aleksandra Ochirova· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMolecular Biology

David LandoORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 25, 2025

HP1β and densely packed chromatin form separate microdomains in mouse ES cells, which are reconfigured upon exit from naive pluripotency

Aleksandra Ochirova, Devina Shah, Ziwei Zhang…·Ernest D. Laue

DOI 10.1101/2025.08.25.671447

𝕏 PostBluesky

Developmental BiologyMolecular CellPeer-reviewedMar 14, 2024

Enhancer-promoter interactions are reconfigured through the formation of long-range multiway chromatin hubs as mouse ES cells exit pluripotency

David Lando, Xiaoyan Ma, Yang Cao…·Ernest D. Laue

The paper studies 3D genome structure changes in single mouse ES cells exiting pluripotency, finding reorganization of enhancer-promoter interactions through multiway chromatin hubs.

27 citations

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 31, 2023

High changing curvature regions detect chromatin enrichment in single cell data

Giulia Amici, Andrea Papale, David Lando…·David Holcman

This study identifies high changing curvature (HCC) regions in Hi-C data that correlate with gene expression and CTCF density, showing cell-to-cell variability.

DOI 10.1101/2023.03.31.535120

Hi-Cstatistical model

𝕏 PostBluesky